Abstract Search

ea0081p166 | Pituitary and Neuroendocrinology | ECE2022

Pasireotide imaging study: magnetic resonance imaging as a predictor of therapeutic response in acromegaly

Ruiz Sabina , Venegas Moreno Eva , Gil Joan , CAMARA ROSA , Biagetti Betina , Angeles Galvez Moreno Maria , Maraver Silvia , Gonzalez-Molero Inmaculada , Pico-Alfonso Antonio , Abellan Galiana Pablo , trincado pablo , Teresa Herrera Arranz Maria , Olvera Pilar , Xifra Villarroya Gemma , Bernabeu Ignacio , Azriel Mira Sharona , Garcia-GarciA-Doncel Lourdes , Jorda Mireia , Valassi Elena , Puig-Domingo Manel

Background: T2-weighted magnetic resonance imaging (MRI) signal has been recently linked with a better tumor response to pasireotide treatment in patients with acromegaly (ACRO). Our aim was to evaluate the prevalence of this radiological feature and its association to therapeutic outcomes in a large cohort of ACRO patients treated with pasireotide.Methods: A retrospective multicentre study was performed in 15 Spanish tertiary university hospitals includ...

4 shares

ea0090p411 | Pituitary and Neuroendocrinology | ECE2023

Usefulness of the short version of the acute octreotide test for prediction of first-generation somatostatin receptor ligands response in acromegaly: a validation study with the ACROFAST cohort

Marques-Pamies Montserrat , Gil Joan , Jorda Mireia , Valassi Elena , Biagetti Betina , Hernandez Marta , Gimenez-Palop Olga , Martinez Silvia , Carrato Cristina , Villar Taibo Rocio , Araujo-Castro Marta , Blanco Concepcion , Simon Inmaculada , Simo-Servat Andreu , Xifra Villarroya Gemma , Vazquez San Miguel Federico , Pavon Isabel , Garcia Centeno Rogelio , Zavala Roxana , Alexandra Hanzu Felicia , Mora Mireia , Aulinas Maso Ana , Vilarrasa N , Soledad Librizzi Maria , Paz De Miguel Novoa Maria , Alvarez-Escola Cristina , Pico-Alfonso Antonio , Antonio Sampedro-Nunez Miguel , Salinas Vert Isabel , Fajardo-Montanana Carmen , Camara-Gomez Rosa , Bernabeu Ignacio , Webb Susan , Marazuela Monica , Puig-Domingo Manel

We previously described a short version of the acute octreotide test (sAOT) for predicting somatostatin receptor ligands (SRLs) response in patients with acromegaly1. In the present work, we prospectively reassess the sAOT ability to identify SRLs response in patients from the ACROFAST study using the current GH standards and control criteria and we also correlate sAOT values with E-cadherin tumor expression. Methods: Patients from the ACROFAS...

1 shares

Endocrine Abstracts

Pasireotide imaging study: magnetic resonance imaging as a predictor of therapeutic response in acromegaly

Usefulness of the short version of the acute octreotide test for prediction of first-generation somatostatin receptor ligands response in acromegaly: a validation study with the ACROFAST cohort

BiosciAbstracts